Located in the sewers of Darktown.
Found in a chest after defeating Eveline in the On The Loose quest.
"A rune that increases all existing damage. A weapon can only bear one Rune of Devastation."
Cost 75s 0c 3 Lyrium 4 Silverite 4 Orichalcum 1 Dragon's Blood
The effect is superior on stronger weapons:
- Weapon and Shield/Dual Weapon: +8% damage
- Two-Handed/Archery/Staves: +10% damage