There may be a brief cutscene with Isabela approached at the bar by a man with a very bad pickup line. If you have completed a romance with a character other than Isabela, she will comment on it. Allowing her to make the joke will result in Isabela: friendship (+5). Refusing will result in Isabela: rivalry (+5). This is separate from A Ship for Isabela and may also occur before Questioning Beliefs (Isabela Act 2), depending on which order you complete the quests and the romance.
The following dialogue options are available:
"It reminded me of you."
"It's not cute."
"The best thing is below decks." (Flirt)
On friendship path: Isabela: friendship (+10) (all dialogue options)
On rivalry path: Isabela: rivalry (+10) (all dialogue options)