There may be a brief cutscene with Isabela approached at the bar by a man with a very bad pickup line. If you have completed a romance with a character other than Isabela, she will comment on it. Allowing her to make the joke will result in Isabela: friendship (+5). Refusing will result in Isabela: rivalry (+5). This is separate from A Ship for Isabela and may also occur before Questioning Beliefs (Isabela Act 2), depending on which order you complete the quests and the romance.
The following dialogue options are available on the friendship path:
"It reminded me of you."
"It's not cute."
"The best thing is below decks." (Flirt)
The following dialogue options are available on the rivalry path: